Poorly Soluble Drugs
How can we improve dissolution, solubility and bioavailability?

15th - 16th April 2009, The Lakeside Centre, Aston University, Birmingham, UK

 
Poor bioavailability of active compounds is a major problem in drug delivery research and development. Often the reason for this is poor aqueous solubility of the drug. For most pharmaceutical companies many drugs in the pipeline fall into class II of the biopharmaceutical classification systems. Depending on the properties of the molecule, these compounds require different formulation strategies to increase their dissolution rate, solubility, and ultimately bioavailability. This workshop will give an overview about the various formulation strategies that may be used to improve bioavailability of poorly water soluble drugs. Industrial and academic perspectives on the link between dissolution, solubility and bioavailability will be given and recent developments in the formulation of these problem drugs will be discussed.
 

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